This article comparatively analyzes the perspectives of Sadr al-Din Muhammad Shirazi (Mulla Sadra) and Immanuel Kant on religious experience and divine knowledge. Mulla Sadra, drawing upon his ontological foundations such as the primacy of existence (asalat al-wujud), substantial motion of the soul, and unmediated knowledge (ilm huduri), posits the possibility of direct and intuitive apprehension of God as the pinnacle of human cognition. In contrast, Kant, with his critical epistemology, delineates the limits of theoretical reason for metaphysical knowledge, including that of God, deeming any theoretical knowledge of the transcendent realm impossible. Nevertheless, Kant opens the door for moral faith in God within the domain of practical reason. This comparison reveals that despite both philosophers acknowledging the limitations of pure discursive reason, their approaches ultimately lead to fundamentally different conclusions regarding the possibility and nature of divine knowledge. These disparities highlight the richness of discussions in the philosophy of religion and Islamic philosophy when confronting this fundamental question And it leaves the way open for further exploration.